Fifth Disease and Daycare: Rash, Contagion and Return

Updated November 2026.

Fifth disease is a mild viral illness that often causes bright red cheeks, like a "slapped cheek," followed by a lacy rash on the body. By the time the rash appears, a child is usually no longer contagious, so most children with fifth disease can stay in daycare if they feel well and have no fever. Pregnant parents and staff who were exposed should call their doctor.

Here is what to know about fifth disease in babies, toddlers and preschoolers.

What is fifth disease?

Fifth disease is caused by parvovirus B19. It spreads through respiratory droplets, such as coughs, sneezes and saliva, mostly in the days before the rash appears. It is most common in school-age children, but younger children in group care get it too, and outbreaks are more common in late winter and spring.

Signs of fifth disease

Early cold-like symptoms: low fever, runny nose, headache or tiredness. This is when the illness spreads.
"Slapped cheek" rash: bright red cheeks a few days to a week later.
Lacy body rash: a pink, lace-like rash on the arms, legs, chest or back that can come and go for a few weeks, especially with heat, sun or a warm bath.
Some children have no symptoms at all.

Can my child go to daycare with fifth disease?

Usually yes. By the time the slapped-cheek rash shows up, most children are no longer contagious. Pediatric guidance generally does not call for keeping children with fifth disease out of child care once the rash appears, as long as they feel well.

Keep your child home if they have a fever, or if they are too sick to take part in the day. Illinois daycare centers screen children daily and exclude children with a rash plus fever, or fever with a change in behavior, until symptoms improve or a doctor clears them. A rash with a fever should always be checked by a doctor. Read our guide to daycare fever rules.

Why pregnant people should call their doctor

Most adults have had fifth disease and are immune. In a small number of pregnancies, infection can affect the baby. If you or a staff member are pregnant and have been around a child with fifth disease, call your health care provider. They may suggest a blood test to check for immunity.

People with certain blood disorders, such as sickle cell disease, or weakened immune systems should also call their doctor after an exposure.

Should I tell the daycare?

Yes. Let the center know if your child has fifth disease. Some centers notify families in the classroom so that pregnant parents and staff can talk to their doctors.

Care at home

Rest and fluids
Ask your pediatrician about fever or pain medicine and the right dose for your child
Never give aspirin to children
The rash does not need treatment. Keep your child cool if heat makes it flare.

When to call the doctor

Your child has a fever with a rash
Your child seems very tired, pale or sick
Your child has a blood disorder or weak immune system
The rash looks purple, bruise-like or does not fade when pressed. Get emergency care.

For general sick-day rules, see how often daycare kids get sick.

Frequently asked questions

Is fifth disease contagious once the rash appears?

Usually not. Children are most contagious before the rash, during the cold-like stage.

Can my child go to daycare with a slapped-cheek rash?

Usually yes, if they have no fever and feel well enough to take part.

How long does the rash last?

The cheek rash fades in a few days. The lacy body rash can come and go for 1 to 3 weeks.

Is fifth disease dangerous in pregnancy?

Usually not, but it can cause problems in a small number of pregnancies. Pregnant people who are exposed should call their doctor.

When a child gets sick at Children's Land

If a child becomes sick during the day at Children's Land, the director calls the designated adult from the Emergency Information Form, and the child rests away from the group until pickup. Learn about our preschool program, find a location, or contact us.

Fifth Disease and Daycare: Rash, Contagion and Return